Self‐Plugging Microneedle (SPM) for Intravitreal Drug Delivery (Adv. Healthcare Mater. 12/2022)
نویسندگان
چکیده
Self-Plugging Microneedles In article number 2102599, Jeong Hun Kim, WonHyoung Ryu, Ali Khademhosseini, and co-workers, develop self-plugging microneedles (SPM) for intravitreal injection. Once injected, the end of SPM is swollen to seal incision due injection rest delivers drugs desired duration. Unlike general injections, doesn't need additional sealing procedures, so this manner lowers possibility infection cost operation.
منابع مشابه
A microneedle roller for transdermal drug delivery.
Microneedle rollers have been used to treat large areas of skin for cosmetic purposes and to increase skin permeability for drug delivery. In this study, we introduce a polymer microneedle roller fabricated by inclined rotational UV lithography, replicated by micromolding hydrophobic polylactic acid and hydrophilic carboxy-methyl-cellulose. These microneedles created micron-scale holes in human...
متن کاملMicroneedle Coating Techniques for Transdermal Drug Delivery
Drug administration via the transdermal route is an evolving field that provides an alternative to oral and parenteral routes of therapy. Several microneedle (MN) based approaches have been developed. Among these, coated MNs (typically where drug is deposited on MN tips) are a minimally invasive method to deliver drugs and vaccines through the skin. In this review, we describe several processes...
متن کاملMicroneedle-based drug delivery systems: microfabrication, drug delivery, and safety.
Many promising therapeutic agents are limited by their inability to reach the systemic circulation, due to the excellent barrier properties of biological membranes, such as the stratum corneum (SC) of the skin or the sclera/cornea of the eye and others. The outermost layer of the skin, the SC, is the principal barrier to topically-applied medications. The intact SC thus provides the main barrie...
متن کاملMicroneedle-mediated Transdermal and Intradermal Drug Delivery
Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transderma...
متن کاملMicroneedle-mediated Transdermal and Intradermal Drug Delivery
Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transderma...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Advanced Healthcare Materials
سال: 2022
ISSN: ['2192-2640', '2192-2659']
DOI: https://doi.org/10.1002/adhm.202270068